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Bitter Sophora Root Extract

Bitter Sophora Root Extract

【Product Name】 Sophora extract [English name] Radix Flavescentis Extract; Lighiyellow Sophora Root P.E [Latin name] Radix Sophorae Flavescentis 【Molecular formula】 C15H24N2O; 【Molecular Weight】 248.36 【Product Specifications】 10: 1; Matrine 0.5% ~ 98% 【Color】 brownish yellow powder Odor: special...

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【Product Name】 Sophora extract

[English name] Radix Flavescentis Extract; Lighiyellow Sophora Root P.E

[Latin name] Radix Sophorae Flavescentis

【Molecular formula】 C15H24N2O;

【Molecular Weight】 248.36

【Product Specifications】 10: 1; Matrine 0.5% ~ 98%

【Color】 brownish yellow powder

Odor: special smell

【Product number】 100% through 80 mesh sieve

【Detection】 tlc / HPLC

【Product Properties】 brown yellow fine powder

【Solubility】: Ethanol, chloroform, toluene, benzene is very easy to dissolve, soluble in acetone, dissolved in water,

In hot water, slightly soluble in petroleum ether.

【Product packaging】: 1kg / aluminum foil bags, 25kg / cardboard drums; can be customized according to customer requirements.

Storage conditions: Shading should be sealed, stored in a dry, cool, well-ventilated place, valid for two years.

Sophora extract efficacy:

1. Protect the role of gastric mucosa

Sophora extract on hydrochloric acid, ethanol, indomethacin-induced gastric mucosal injury has a significant protective effect, the main component is flavanones.

Anti-inflammatory effect

Matrine on a variety of inflammatory agents caused by acute exudative inflammation were significantly antagonistic use, similar to the role of hydrocortisone. Matrine has a stabilizing effect on the erythrocyte membrane, and drugs that have a stabilizing effect on erythrocytes often have a stabilizing effect on the lysosomal membrane, thereby reducing the release of inflammatory mediators and achieving the purpose of anti-inflammatory.

Anti-tumor effect

Matrine had a significant inhibitory effect on the multiplicity of hematopoietic progenitor colony formation in the periphery of chronic myeloid leukemia. Sophora decoction on cultured human promyelocytic leukemia cells, can significantly induce leukemia cells to monocyte-macrophage direction differentiation.

4. Asthma expectorant effect

Matrine is mainly through the excitement of β receptors, especially the excitement of the central β receptor, the lifting of bronchial spasm and inhibit the release of antibodies and slowly reacting substances to produce antiasthmatic effect.

5. Anti-allergic effects

Matrine reduced the release of hypersensitive mediators and inhibited the proliferation of 50% OT cells at a concentration of 0.55-0.56 mg / ml; the IL-2 production was inhibited at a concentration of 0.1 mg / kg.

6. Immunosuppressive effect

Matrine and oxymatrine have inhibitory effects on immune function in mice.

Anti-fungal effect

Sophorae decoction of the common skin fungus inhibitory effect.

8. Bacteriostatic effect

Sophora flavescens immersion of Staphylococcus aureus, Pseudomonas aeruginosa, such as Mycobacterium tuberculosis have inhibitory effect.


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