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Radix Notoginseng Extract

Radix Notoginseng Extract

【Product Name】: Notoginseng extract, Panax notoginseng 【English name】: Radix Notoginseng P.E. 【Alias】: Ginseng Panax, Tianqi, Panlong VII, the gold does not change, the lion head mountain lacquer, ginseng, Yunnan thirty-seven, soil thirty-seven, blood mountain grass, June leaching, blood...

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【Product Name】: Notoginseng extract, Panax notoginseng

【English name】: Radix Notoginseng P.E.

【Alias】: Ginseng Panax, Tianqi, Panlong VII, the gold does not change, the lion head mountain lacquer, ginseng, Yunnan thirty-seven, soil thirty-seven, blood mountain grass, June leaching, blood ginseng, Grass, copper skull.

[Extraction site]: Panax notoginseng Panax notoginseng (Burk.) F.H.Chen root

The main components: Contains saponins, mainly ginsenosides Rb1, Rg1, Rg2 and a small amount of ginsenosides Ra, Rb2, Rb and Re.

【Formula】 C47H80O17

【Specification】: 10: 1 20: 1 30: 1; Panax notoginseng saponin 10-80%

Appearance: brown powder

Odor: special

【Product Properties】: This product is light yellow amorphous powder, bitter, slightly sweet, there is cited wet. This product is soluble in methanol, ethanol and water, insoluble in acetone, ether and benzene, easy to absorb moisture.

【Detection】: HPLC / UV

[Storage]: Store in a cool dry, dark, avoid high temperatures.

【Packing】: 1kg / aluminum foil bag, 25kg / cardboard drum (with double plastic bag, coat cardboard drum).

[Shelf life]: 12 months.

 

effect

(1) Anti-arrhythmic effect: Panax notoginseng saponins on all kinds of drug-induced arrhythmia, have a protective effect.

(2) anti-atherosclerotic effect: Panax notoginseng saponins can inhibit 3H-thymidine incorporation in vitro cultured rabbit aortic smooth muscle cells and cell proliferation, can significantly inhibit the low concentration of high-fat serum 3H-thymidine Nucleosides into cells to promote the role of value-added, suggesting that notoginsenoside has an impact on the occurrence and development of atherosclerosis.

(3) hypoxia and anti-shock effect: notoginseng total saponin can significantly reduce myocardial oxygen consumption and oxygen utilization rate, improve myocardial oxygen metabolism; increase the body's tolerance to blood loss, can reduce cardiac afterload, Reduce myocardial blood pump resistance, significantly prolong the survival time of shock animals.

(4) the impact on cerebral ischemia: Panax notoginseng can expand cerebral blood vessels, increase cerebral blood flow.

(5) the impact on blood pressure: Panax notoginseng can significantly reduce canine arterial blood pressure and total peripheral resistance. The effect of Panax notoginsenoside on the expansion of the internal carotid artery is weaker than that on the expansion of the pre-mesenteric artery, with obvious role of selectivity.

(6) the impact on the heart: Panax notoginseng on the heart has a negative frequency and negative inotropic effect, and showed a clear dose and frequency dependence, and its negative frequency effect and block the slow calcium channel. Intravenous Panax notoginseng saponins, can fight against the pituitrin-induced myocardial ischemia effect.

(7) anti-coronary heart disease effect: 37 on coronary heart disease, angina has a good effect. Studies have shown that the ethanol extract of Brassica napus can increase the coronary flow, increase myocardial nutritional blood flow and reduce myocardial oxygen consumption, thereby improving coronary heart disease patients with blood supply, oxygen supply, myocardial oxygen recovery and oxygen consumption between Balance. Panax notoginseng injection can also increase coronary blood flow, reduce myocardial oxygen consumption. Its anti-coronary active ingredient is mainly contained flavonoid glycosides and notoginsenosides.


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