【Product Name】: Curcumin [Source]: Turmeric stems from the rhizome of turmeric ginger branch. The main components: curcumin, volatile oil, ginger flavonoids and ginger ene, borneol and sesquiterpene alcohol 【Product Specifications】: Curcumin 99% 【Main Specifications】: Curcumin 99% (HPLC) Odor:...Send Inquiry
【Product Name】: Curcumin
[Source]: Turmeric stems from the rhizome of turmeric ginger branch.
The main components: curcumin, volatile oil, ginger flavonoids and ginger ene, borneol and sesquiterpene alcohol
【Product Specifications】: Curcumin 99%
【Main Specifications】: Curcumin 99% (HPLC)
[Test method]: TLC / HPLC
【Solubility】: Do not dissolve in water and ether, soluble in ethanol and acetic acid.
【Formula】: curcumin Curcumin: C21H20O6
【Product Properties】: orange yellow crystalline powder, melting point 183 °
[Product number]: 100% through 80 mesh sieve
【Packing】 1 kg / aluminum foil bag 25 kg / cardboard drum
Storage conditions should be sealed light, stored in a dry, cool, well-ventilated place, valid for two years.
Turmeric extract is the main bioactive substances curcumin and curcumin, with antihypertensive, hypolipidemic, gallbladder, anti-bacterial, anti-inflammatory and antioxidant effects. Curcumin is a very important pigment compound that prevents the auto-oxidation of linoleic acid in foods and has anti-cancer and anti-cancer functions. It has been widely used as a natural high-quality food pigment.
1. Inhibit tumor growth
Curcumin alcohol extract had cytotoxic effect on lymphocytes and Dalton lymphoma cells. Intraperitoneal injection of curcumin liposomes could inhibit the formation of mouse Dalton lymphoma cells and increase the survival rate of mice. 12-O-tetradecanoylphorbol acetate TPA is a tumor promoter that can be used to produce skin tumors in mice. For example, when curcumin is combined with TPA topically applied to mice twice a week for 20 weeks and curcumin is previously inhibited by 7,12-dimethylbenzene [a] anthracene as a tumor promoter, curcumin inhibits TPA-producing tumors number.
2. gallbladder effect
Turmeric decoction and infusion can increase canine bile secretion, so that bile components return to normal and increase gallbladder contraction, its role is weak and lasting, sustainable 1 to 2 hours, its choleretic effect and its lipid-lowering. Curcumin or its sodium salt has a gallbladder effect, intravenous injection in dogs, can reduce the content of solid content and increase bile secretion. 50% turmeric decoction can promote appetite.
Curcumin can significantly antagonize NIH mouse brain, heart, liver, kidney and spleen homogenate peroxidation, in a certain dose range, the intensity of a dose-dependent relationship.
4. Anti-pathogenic microorganisms and protozoa effect
Curcuma alcohol extract and its active ingredients can inhibit the growth of most bacteria causing cholecystitis, including Sarcina, Gaffkya, Corynebacterium, Streptococcus and other bacilli, but even if the application of high Concentration of all tested Gram-negative bacilli, some yeasts and mold are not sensitive. Turmeric alcohol extract and volatile oil with bactericidal effect, and curcumin staphylococci only bacteriostat. Turmeric ether and chloroform extract in vitro inhibition of several pathogenic skin fungi, turmeric volatile oil 1:10 can inhibit the growth of different pathogenic fungi. Curcumin alcohol extract has the effect of anti-host amoeba in vitro.
5. Anti-mutation effect
Rats were fed various doses of turmeric (feed mix) for 3 months, then peritoneal injection of benzopyrene or 3-methylcholanthrene. Salmonella typhimurium was used to detect the mutagenicity of urine. When the mice were fed with more than 0.5% turmeric, the mutagenicity of benzopyrene or 3-methylcholanthrene was inhibited, and turmeric did not affect the food intake and weight gain of rats , Histological examination also did not change. Curcumin can inhibit the mutagenicity of several environmental mutagens (cigar, cigarette smoke, tobacco and malt extract, benzopyrene, dimethylbenz-anthracene, etc.), and in a dose-response relationship, curcumin can change Mutagenesis of the original metabolic activation and detoxification.
6. Antibacterial, anti-inflammatory effect
Curcumin and volatile oil part of Staphylococcus aureus has good antibacterial activity. Curcuma extract on a variety of fungi inhibition; curcumin mouse and rat experimental inflammation was significantly inhibited rheumatoid arthritis has anti-inflammatory effect, to reduce spermatic cord edema and tenderness have a certain effect .
7. Anti-fertility effects
Turmeric extract has a clear stopping effect on pregnancy in mice, rats and rabbits, it can antagonize the activity of progesterone and contract the uterus. Experiments show that turmeric decoction and infusion on mice and guinea pigs in vitro uterine and uterine fistulas are excited. Paroxysmal uterine contractions to strengthen, and can be maintained for 5 to 7 hours, showing anti-pregnancy effect.
8. The role of the gastrointestinal tract
Rat ethanol administration of turmeric extract on the stress of low temperature restraint, pyloric ligation and indomethacin, reserpine and other ulcers caused by significant anti-ulcer effect on cyst rupture caused by gastric injury showed a very significant protection effect. Turmeric ethanol extract not only significantly thicken the gastric mucosal wall, but also restore the content of non-protein sulfhydryl group in rat gastric gland.
The role of the cardiovascular system
Curcumin alcohol extract in vitro and in vivo frog heart was inhibited. Intravenous injection can cause blood pressure, respiratory excitement. The antihypertensive effect is not affected by atropine and cut off the vagus nerve, such as the first injection of ergot flow extract can make its role in antihypertensive effect of antihypertensive. Curcumin can increase myocardial nutritional blood flow in mice. Turmeric extract can antagonize pituitrin-induced myocardial ischemia in rats.
10. hypolipidemic effect
Turmeric extract, curcumin, volatile oil oral, experimental hyperlipidemic rats and rabbits have significant serum cholesterol and β-lipoprotein and other effects, and can reduce hepatic cholesterol, correct β-and α-lipoprotein The proportion of disorders, but no effect on endogenous cholesterol, but also reduce the aorta of rats with hyperlipemia of the liver triglyceride and cholesterol content.
11. Anti-clotting and inhibition of platelet aggregation
Administration of curcumin alcohol extract or curcumin can inhibit ADP-induced platelet aggregation in hyperlipidemic rats. Curcumin enhances fibrinolytic activity. Turmeric ether extract can inhibit arachidonic acid-induced human platelet aggregation and thromboxane B2 (TXB2) production, while making the product of the enzyme catalyzed by lipoxygenase increased.
12. Other roles
Turmeric extract and curcumin can enhance fibrinolytic activity, protect the liver, anti-liver fibrosis, turmeric decoction analgesic effect on postoperative inflammation and pain in the operation site analgesic effect; turmeric decoction on hepatitis virus inhibition, And to improve the effect of liver parenchymal lesions.